A hybrid imaging system commonly used in nuclear medicine combines CT with which modality?

• A. CT and SPECT
• B. CT and MRI
• C. PET and MRI
• D. Ultrasound and CT

Answer: (A)

Hybrid imaging in nuclear medicine blends functional information from radionuclide imaging with precise anatomical detail from CT. The combination of CT with SPECT creates a SPECT/CT system, which pairs the functional map of tracer distribution provided by SPECT with CT’s high-resolution anatomy. This pairing lets clinicians see not only where a abnormal function is happening but also exactly where it sits in the body, improving localization, interpretation, and the accuracy of attenuation correction for the functional data. While PET/CT is also a common hybrid, the option that matches CT with a radionuclide functional modality in this question is SPECT, making the combination CT with SPECT the correct choice. Other pairings like CT with MRI or Ultrasound with CT don’t provide the same integrated functional-anatomical fusion used in this context.